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1

Actin-independent exclusion of CD95 by PI3K/AKT signalling: Implications for apoptosis

Mathieu Pizon, Hariniaina Rampanarivo, Sébastien Tauzin, Benjamin Chaigne-Delalande, Sophie Daburon, Michel Castroviejo, Patrick Moreau, Jean-François Moreau, Patrick Legembre

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 540 KB

english, 2011

2

Flt3-ligand induces adhesion of haematopoietic progenitor cells via a very late antigen (VLA)-4- and VLA-5-dependent mechanism

Anne Solanilla, Christophe Grosset, Pascale Duchez, Patrick Legembre, Vincent Pitard, Maryse Dupouy, Françis Belloc, Jean-François Viallard, Josy Reiffers, Jean-Michel Boiron, Laure Coulombel, Jean Ri

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

3

Rewinding the DISC

Benjamin Chaigne-Delalande, Jean-François Moreau, Patrick Legembre

Journal:

Archivum Immunologiae et Therapiae Experimentalis

Year:

2008

Language:

english

File:

PDF, 1.02 MB

english, 2008

4

CD95 et caspase-12 dans la réponse immunitaire

C. Behr, M. Pizon, P. Legembre

Journal:

Journal africain du cancer / African Journal of Cancer

Year:

2009

File:

PDF, 98 KB

2009

5

CD95 engagement mediates actin-independent and -dependent apoptotic signals

Chaigne-Delalande, B, Mahfouf, W, Daburon, S, Moreau, J-F, Legembre, P

Journal:

Cell Death & Differentiation

Year:

2009

Language:

english

File:

PDF, 906 KB

english, 2009

6

The HA tag is cleaved and loses immunoreactivity during apoptosis

Schembri, Laura, Dalibart, Renee, Tomasello, Flora, Legembre, Patrick, Ichas, François, De Giorgi, Francesca

Journal:

Year:

2007

Language:

english

File:

PDF, 198 KB

english, 2007

7

Potentiation of Fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked Fas

Legembre, P, Moreau, P, Daburon, S, Moreau, J-F, Taupin, J-L

Journal:

Cell Death & Differentiation

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

8

CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells

Barnhart, Bryan C, Legembre, Patrick, Pietras, Eric, Bubici, Concetta, Franzoso, Guido, Peter, Marcus E

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 511 KB

english, 2004

9

Induction of apoptosis and activation of NF-κB by CD95 require different signalling thresholds

Legembre, Patrick, Barnhart, Bryan C, Zheng, Lixin, Vijayan, Shrijay, Straus, Stephen E, Puck, Jennifer, Dale, Janet K, Lenardo, Michael, Peter, Marcus E

Journal:

Year:

2004

Language:

english

File:

PDF, 150 KB

english, 2004

10

CD95-mediated cell signaling in cancer: mutations and post-translational modulations

Sébastien Tauzin, Laure Debure, Jean-François Moreau, Patrick Legembre

Journal:

Cellular and Molecular Life Sciences

Year:

2012

Language:

english

File:

PDF, 613 KB

english, 2012

11

Does CD95 have tumor promoting activities?

Marcus E. Peter, Patrick Legembre, Bryan C. Barnhart

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2005

Language:

english

File:

PDF, 454 KB

english, 2005

12

Corrigendum to “Does CD95 have tumor promoting activities?” [Biochim. Biophys. Acta 1755 (2005) 25–36]

Marcus E. Peter, Patrick Legembre, Bryan C. Barnhart

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2007

Language:

english

File:

PDF, 411 KB

english, 2007

13

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells

Amélie Rebillard, Sandrine Jouan-Lanhouet, Elodie Jouan, Patrick Legembre, Mathieu Pizon, Odile Sergent, David Gilot, Xavier Tekpli, Dominique Lagadic-Gossmann, Marie-Thérèse Dimanche-Boitrel

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 692 KB

english, 2010

14

S-Nitrosylation of the Death Receptor Fas Promotes Fas Ligand–Mediated Apoptosis in Cancer Cells

Lissbeth Leon-Bollotte, Selvakumar Subramaniam, Olivier Cauvard, Stéphanie Plenchette–Colas, Catherine Paul, Cindy Godard, Antonio Martinez–Ruiz, Patrick Legembre, Jean–François Jeannin, Ali Bettaieb

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 2.77 MB

english, 2011

15

The CD95/CD95L signaling pathway: A role in carcinogenesis

Fouqué, Amélie, Debure, Laure, Legembre, Patrick

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

16

Downregulation of ceramide synthase-6 during epithelial-to-mesenchymal transition reduces plasma membrane fluidity and cancer cell motility

Edmond, V, Dufour, F, Poiroux, G, Shoji, K, Malleter, M, Fouqué, A, Tauzin, S, Rimokh, R, Sergent, O, Penna, A, Dupuy, A, Levade, T, Theret, N, Micheau, O, Ségui, B, Legembre, P

Journal:

Year:

2015

Language:

english

File:

PDF, 3.43 MB

english, 2015

17

Cutting Edge: SDS-Stable Fas Microaggregates: An Early Event of Fas Activation Occurring with Agonistic Anti-Fas Antibody but Not with Fas Ligand

Legembre, P., Beneteau, M., Daburon, S., Moreau, J.-F., Taupin, J.-L.

Journal:

The Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 394 KB

english, 2003

18

Cutting Edge: Modulation of Fas-Mediated Apoptosis by Lipid Rafts in T Lymphocytes

Legembre, P., Daburon, S., Moreau, P., Moreau, J.-F., Taupin, J.-L.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 334 KB

english, 2006

19

CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) 2, and prevents death-inducing signaling complex formation

Khadra, N., Bresson-Bepoldin, L., Penna, A., Chaigne-Delalande, B., Segui, B., Levade, T., Vacher, A.-M., Reiffers, J., Ducret, T., Moreau, J.-F., Cahalan, M. D., Vacher, P., Legembre, P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

20

Identification of SNF1/AMP Kinase-related Kinase as an NF- B-regulated Anti-apoptotic Kinase Involved in CD95-induced Motility and Invasiveness

Legembre, P., Schickel, R., Barnhart, B. C., Peter, M. E.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 736 KB

english, 2004

21

Localization of Fas/CD95 into the Lipid Rafts on Down-Modulation of the Phosphatidylinositol 3-Kinase Signaling Pathway

Beneteau, M., Pizon, M., Chaigne-Delalande, B., Daburon, S., Moreau, P., De Giorgi, F., Ichas, F., Rebillard, A., Dimanche-Boitrel, M.-T., Taupin, J.-L., Moreau, J.-F., Legembre, P.

Journal:

Molecular Cancer Research

Year:

2008

Language:

english

File:

PDF, 703 KB

english, 2008

22

Two CD95 tumor classes with different sensitivities to antitumor drugs

Algeciras-Schimnich, A., Pietras, E. M., Barnhart, B. C., Legembre, P., Vijayan, S., Holbeck, S. L., Peter, M. E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2003

Language:

english

File:

PDF, 434 KB

english, 2003

23

Amplification of Fas-Mediated Apoptosis in Type II Cells via Microdomain Recruitment

Legembre, P., Daburon, S., Moreau, P., Ichas, F., de Giorgi, F., Moreau, J.-F., Taupin, J.-L.

Journal:

Molecular and Cellular Biology

Year:

2005

Language:

english

File:

PDF, 690 KB

english, 2005

24

The Immunosuppressor Mycophenolic Acid Kills Activated Lymphocytes by Inducing a Nonclassical Actin-Dependent Necrotic Signal

Chaigne-Delalande, B., Guidicelli, G., Couzi, L., Merville, P., Mahfouf, W., Bouchet, S., Molimard, M., Pinson, B., Moreau, J.-F., Legembre, P.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 1.21 MB

english, 2008

25

Dominant-Negative Fas Mutation Is Reversed by Down-expression of c-FLIP

Beneteau, M., Daburon, S., Moreau, J.-F., Taupin, J.-L., Legembre, P.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 510 KB

english, 2007

26

R9: Potentialisation de la réponse apoptotique au Rituximab (RTX) dans les lymphomes B non hodgkinien : rôle du calcium

Bresson-Bépoldin, L., Vacher, A.M., Pomier, C., Pineau, R., Soubeyran, I., Soubeyran, P., Legembre, P., Vacher, P.

Journal:

Bulletin du Cancer

Year:

2010

Language:

french

File:

PDF, 80 KB

french, 2010

27

Mycophenolic Acid Overcomes Imatinib and Nilotinib Resistance of Chronic Myeloid Leukemia Cells by Apoptosis or a Senescent-Like Cell Cycle Arrest

Drullion, Claire, Lagarde, Valérie, Gioia, Romain, Legembre, Patrick, Priault, Muriel, Cardinaud, Bruno, Lippert, Eric, Mahon, François-Xavier, Pasquet, Jean-Max

Journal:

Leukemia Research and Treatment

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

28

The CD95 signaling pathway

Penna, Aubin, Khadra, Nadine, Tauzin, Sébastien, Vacher, Pierre, Legembre, Patrick

Journal:

Communicative & Integrative Biology

Year:

2012

Language:

english

File:

PDF, 793 KB

english, 2012

29

An atypical necrotic signal induced by immunosuppressive and anti-viral agents

Chaigne-Delalande, Benjamin, Guidicelli, Gwendalline, Couzi, Lionel, Legembre, Patrick

Journal:

Year:

2009

Language:

english

File:

PDF, 472 KB

english, 2009

30

The relevance of NF-?B for CD95 Signaling in Tumor Cells

Legembre, Patrick, Barnhart, Bryan C., Peter, Marcus E.

Journal:

Year:

2004

Language:

english

File:

PDF, 927 KB

english, 2004

31

Editorial [Hot topic: Stresses, Death Receptors and Plasma Membrane (Guest Editors: Patrick Legembre and Faustino Mollinedo)]

Legembre, Patrick, Mollinedo, Faustino

Journal:

Recent Patents on Anti-Cancer Drug Discovery

Year:

2011

Language:

english

File:

PDF, 42 KB

english, 2011

32

The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca2+ flux from the endoplasmic reticulum to mitochondria

Fouqué, A, Lepvrier, E, Debure, L, Gouriou, Y, Malleter, M, Delcroix, V, Ovize, M, Ducret, T, Li, C, Hammadi, M, Vacher, P, Legembre, P

Journal:

Cell Death & Differentiation

Year:

2016

Language:

english

File:

PDF, 5.85 MB

english, 2016

33

Does calcium contribute to the CD95 signaling pathway?

Vacher, Pierre, Khadra, Nadine, Vacher, Anne-Marie, Charles, Emilie, Bresson-Bepoldin, Laurence, Legembre, Patrick

Journal:

Anti-Cancer Drugs

Year:

2011

Language:

english

File:

PDF, 231 KB

english, 2011

34

Cyaneodimycin, a Bioactive Compound Isolated from the Culture of Streptomyces cyaneofuscatus Associated with Lichina confinis

Parrot, Delphine, Legrave, Nathalie, Intertaglia, Laurent, Rouaud, Isabelle, Legembre, Patrick, Grube, Martin, Suzuki, Marcelino T., Tomasi, Sophie

Journal:

European Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

35

[Methods in Molecular Biology] CD95 Volume 1557 ||

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 7.91 MB

english, 2017

36

[Methods in Molecular Biology] CD95 Volume 1557 || Isolation of Lipid Rafts Through Discontinuous Sucrose Gradient Centrifugation and Fas/CD95 Death Receptor Localization in Raft Fractions

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 377 KB

english, 2017

37

[Methods in Molecular Biology] CD95 Volume 1557 || Study of the CD95-Mediated Non-apoptotic Signaling Pathway: PI3K

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 284 KB

english, 2017

38

[Methods in Molecular Biology] CD95 Volume 1557 || CD95 and the MRL-lpr Mouse Model

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 174 KB

english, 2017

39

[Methods in Molecular Biology] CD95 Volume 1557 || Production of the Non-apoptotic Metalloprotease-Cleaved CD95L and Its Cytotoxic Recombinant Counterpart Designed Ig-CD95L

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 278 KB

english, 2017

40

[Methods in Molecular Biology] CD95 Volume 1557 || Fluorometric Methods for Detection of Mitochondrial Membrane Depolarization Induced by CD95 Activation

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 565 KB

english, 2017

41

[Methods in Molecular Biology] CD95 Volume 1557 || Boyden Chamber Assay to Study of Cell Migration Induced by Metalloprotease Cleaved-CD95L

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 390 KB

english, 2017

42

[Methods in Molecular Biology] CD95 Volume 1557 || Exploration of Fas S-Nitrosylation by the Biotin Switch Assay

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 243 KB

english, 2017

43

[Methods in Molecular Biology] CD95 Volume 1557 || Proximity Ligation Assay (PLA) to Evaluate DISC and MISC Composition

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 332 KB

english, 2017

44

[Methods in Molecular Biology] CD95 Volume 1557 || Method to Measure Sphingomyelin Synthase Activity Changes in Response to CD95L

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 183 KB

english, 2017

45

[Methods in Molecular Biology] CD95 Volume 1557 || Detection of S-Acylated CD95 by Acyl-Biotin Exchange

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 444 KB

english, 2017

46

[Methods in Molecular Biology] CD95 Volume 1557 || Quantifying CD95/cl-CD95L Implications in Cell Mechanics and Membrane Tension by Atomic Force Microscopy Based Force Measurements

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 523 KB

english, 2017

47

[Methods in Molecular Biology] CD95 Volume 1557 || Liquid Chromatography–High Resolution Mass Spectrometry Method to Study Sphingolipid Metabolism Changes in Response to CD95L

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 173 KB

english, 2017

48

[Methods in Molecular Biology] CD95 Volume 1557 || CD95-Mediated Proton Regulation

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 289 KB

english, 2017

49

[Methods in Molecular Biology] CD95 Volume 1557 || CD95-Mediated Calcium Signaling

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

50

[Methods in Molecular Biology] CD95 Volume 1557 || In Vitro Evaluation of the Apoptosis Function in Human Activated T Cells

Legembre, Patrick

Year:

2017

Language:

english

File:

PDF, 370 KB

english, 2017

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